Clinical Studies on Root Causes of Disease

  1. Oxidative stress, inflammation and cancer: How are they linked?
    PMID: 20840865
  2. Cancer cells and oxidative stress PMID:19252465
  3. The role of oxidative stress in prostate cancer PMID: 21857523 DOI: 10.1097/CEJ.0b013e32834a8002 
  4. Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer  PMID:19149749 DOI: 10.2174/187221309787158371 
  5. Oxidative stress in carcinogenesis: new synthetic compounds with dual effects upon free-radicals and cancer PMID: 23834180 DOI:10.2174/09298673113203690142 
  6. Bioelectric Dysregulation in Cancer Initiation, Promotion and Progression
    PMID: 35359398 PMCID: PMC8964134  DOI: 10.3389/fonc.2022.846917   
  7. Bioelectric signaling: Reprogrammable circuits underlining embryogenesis, regeneration, and cancer
    PMID: 33826908 DOI: 10.1016/j.cell.2021.02.034      
  8. The multifaceted role of reactive oxygen species in tumorigenesis
    PMID: 32358622 DOI: 10.1007/s00018-020-0356-5
  9. Oxidative stress in prostrate cancer
    PMID: 19185987 PMCID: PMC2789743  DOI: 10.10167/j.canlet.2008.12.011 
  10. Endogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer
    PMID: 25525610 PMCID PMC7524426  DOI: 10.4172/2324-9110.S1-002 
  11. Free radicals, metals and antioxidants in oxidative stress-induced cancer
    PMID: 16430879 DOI: 10.1016/j.cbi.2005.12.009 
  12. Mitochondria and cancer
    PMID: 23001348 PMCID: PMC4371788 DOI:10.1038/nrc3365   
  13. Free radicals: properties, sources, targets and their implication in various diseases
    PMID: 25646037 PMCID: PMC4310837  DOI: 10.1007/s1229-014-0446-O 
  14. Role of oxygen free radicals in cancer development
    PMID: 8695238 DOI: 10.1016/0959-8049(95)00531-5    
  15. Role of oxygen radicals in DNA damage and cancer incidence PMID: 15646026 DOI: 10.1023/b:mcbi.0000049134.69131.89    
  16. Oxidative and antioxidative mechanisms in oral cancer and precancel: a review PMID: 24126222 DOI: 10.1016/j.oraloncology.2013.09.011   
  17. Oxidative stress and experimental carcinogenesis PMID: 12587714
  18. Role of oxidative stress and antioxidant network in cutaneous carcinogenesis
    PMID: 15117361 DOI: 10.1111/j.1365-4632.2004.02222.x  
  19. Free radicals in the physiological control of cell function
    PMID: 11773609 DOI: 10.1152/physrev.00018.2001 
  20. Free Radicals, Oxidative Stress-Related Diseases and Antioxidant Supplementation
    PMID: 32827401
  21. Free Radicals and brain aging
    PMID: 15182885 DOI: 10.1016/j.cger.2004.02.005 
  22. Hallmarks of protein oxidative damage in neurodegenerative diseases: focus on Alzheimer’s disease
    PMID: 17273806 DOI: 10.1017/s00726-006-0431-x 
  23. Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview
    PMID: 16183338 DOI: 10.1016/j.jchromb.2005.04.023 
  24. Studies on free radicals, antioxidants, and co-factors
    PMID: 18044138 PMCID: PMC2684512 
  25. Free radicals, oxidative stressed the origin of Parkinson’s disease
    PMID: 10561521 DOI: 10.1016/s0022-510x(99)00191-4. 
  26. Oxidative stress in cells damage process PMID: 19650429
    PMID: 19650429
  27. Free radicals and antioxidants in normal physiological functions and human disease
    PMID: 16978905 DOI: 10.1016/j.biocel.2006.01.001 
  28. Free radicals: properties, sources, targets, and their implication in various diseases
    PMID: 25646037 PMCID: PMC4310837  DOI: 10.1007/s12291-014—0446
  29. Free radicals in the physiological control of cell function
    PMID: 117873609 DOI: 10.1152/physrev.00018.2001
  30. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    PMID: 17051205 PMID: 17051205 DOI: 10.1038/nature05292
  31. Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
    PMID: 31013638 PMID: 31013638 PMCID: PMC6514564 DOI: 10.3390/molecules24081583
  32. Medicinal prospects of antioxidants: A review
    PMID: 31228811  DOI: 10.1016/j.ejmech.2019.06.010
  33. Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders
    PMID: 27809706 DOI: 10.1080/01616412.2016.1251711
  34. Oxidative stress and neurotoxicity
    PMID: 18052107 DOI: 10.1021/tx700210j
  35. Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases
    PMID: 17303344   DOI: 10.1016/j.neuroscience.2006.10.056
  36. Molecular Mechanisms behind Free Radical Scavengers Function against Oxidative Stress
    PMID: 28698499 PMCID: PMC5618079 DOI: 10.3390/antiox6030051
  37. Mitochondria, oxidative stress and neurodegeneration
    PMID: 22669122 DOI: 10.1016/j.jns.2012.05.030
  38. Oxidative stress in Parkinson’s disease and other neurodegenerative disorders
    PMID: 8734302 
  39. Mitochondrial free radical generation oxidative stress, and aging
    PMID: 11035250 DOI: 10.1016/s0891-5849(00)00317-8
  40. Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration
    PMID: 22793257 PMCID: PMC3887431 DOI: 10.1089/ars.2012.4774
  41. Energy metabolism and inflammation in brain aging and Alzheimer’s disease
    PMID: 27154981 PMCID: PMC5094909 doi: 10.1016/j.freeradbiomed.2016.04.200.
  42. Oxidative stress in multiple sclerosis
    PMID: 20120717  
  43. Radical changes in multiple sclerosis pathogenesis
    PMID: 20600869 PMID: 20600869 DOI: 10.1016/j.bbadis.2010.06.011
  44. Antioxidant therapy in multiple sclerosis
    PMID: 18763202 DOI: 10.1080/08923970802331943
  45. The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy
    PMID: 15015004 DOI: 10.1007/s00415-004-0348-9
  46. Oxidative/Nitroxidative Stress and Multiple Sclerosis
    PMID: 32767188 DOI: 10.1007/s12031-020-01672-y
  47. Mitochondriain multiplesclerosis
    PMID: 17981781 DOI: 10.2741/2913
  48. Oxidativestressinduced by lipid peroxidation is related with inflammation of demyelination and neurodegeneration in multiple sclerosis
    PMID: 25277682 DOI: 10.1159/000363515
  49. New Insights into the Role of Oxidative Stress Mechanisms in the Pathophysiology and Treatment of Multiple Sclerosis
     PMID: 27829982 PMCID: PMC5088319 DOI: 10.1155/2016/1973834
  50. New insights in the mechanisms of impaired redox signaling and its interplay with inflammation and immunity in multiple sclerosis
    PMID: 31852206 PMCID: PMC8565962    DOI: 10.33549/physiolres.934276
  51. Inflammation: A New Look at an Old Problem
    PMID: 35562986 PMCID: PMC9100490   DOI: 10.3390/ijms23094596
  52. Mitochondria in Multiple Sclerosis: Molecular Mechanisms of Pathogenesis
    PMID: 28069137 DOI: 10.1016/bs.ircmb.2016.08.003
  53. Free radicals in brain metabolism and pathology
    PMID: 8221024 DOI: 10.1093/oxfordjournals.bmb.a072632
  54. The roles of free radicals in amyotrophic lateral sclerosis
    PMID: 890661 DOI: 10.1007/BF02736837
  55. Free radicals as mediators of neuronal injury
    PMID: 9876873 DOI: 10.1023/a:1020685903186
  56. Oxidative Stress in Autoimmune Diseases: An Under Dealt Malice
    PMID: 32056521 DOI: 10.2174/1389203721666200214111816
  57. Inflammation ,Iron, Energy Failure, and Oxidative Stress in the Pathogenesis of Multiple Sclerosis
     PMID: 26106458 PMCID: PMC4461760  DOI: 10.1155/2015/725370